Книга «Autoantibodies and Autoimmunitiy» представляет собой всеобъемлющий источник информации об аутоантителах и аутоиммунитете. Она охватывает все аспекты биологии аутоантител в одном томе, включая обсуждение иммунологии, экспериментальные модели, клинические особенности и использование аутоантитела в качестве анализаторов в молекулярной и клеточной биологии. Редактор, в настоящее время профессор Центра аутоиммунных заболеваний имени Кейка при Исследовательском институте Скриппса, собрал звездный состав авторов для публикации последних исследований, технологий и приложений.
Во вступительной главе книга охватывает такие темы, как клеточные механизмы выработки аутоантитело, клиническую и диагностическую ценность их использования в человеческих заболеваниях и экспериментальные модели животных для изучения индукции аутоантителои. Том завершается обзором перспектив на будущее. Имея широкий охват, книга привлечет не только иммунологов и клинических врачей, но и исследователей клеточной и молекулярной биологии.
This is the first volume to provide a state-of-the knowledge review on the entire field of autoimmune diseases in one volume, covering the most relevant members of our knowledge base. Immunology, experimental paradigms, clinical features, therapies, and prognosis of specific systems all benefit from analysis with autoantibodies, and current discoveries and development within these areas are reviewed in this conspicuous compilation.
The final product is provided by a distinguished group of talented professionals within the realm of academic, clinical, and research endeavors. A special notice goes towards Prof. Chakravarty, who consolidates all the expertise and findings into a harmonized framework that truly uncovers the dynamic and complex ecosystem that produces autoimmune disorders. It is evident that this volume covers all relevant surfaces while leaving virtually nothing out of scope.
From an autobiographical perspective, I was tasked with the endeavor of writing the introductory chapter. My task after the completion of this phase was made easier by the enjoyable composition of chapters by experts in the field, each chapter injecting unique subjects that when taken together exert an impactful capstone. Specifically, key themes were covered as containment of autoreactive B cells, mediators involved in autoimmune processes, targets for therapies within hypertension and rigidity, clues toward autoimmune reproductive disorders, like infertility, and - not least - assessment of risk factors for autoimmunity at different stages of life. Geared to a global view of fascinating proof, this compendium will draw numerous researchers from across the spectrum of biological and clinical disciplines to learn more about this fascinating phenomenon.
In sum, Autoantibodies & Autoimmunity succeeds in seamlessly placing together threads of immunological, clinical, prognostic, investigational, and curative applications that will illuminate research colleagues' curiosity, while prodding practitioners and patients alike to understand the complexity and untamed potential of the effects of antinuclear autoantibodies within and outside of aberrant behavior. Truly invaluable and indispensable to all areas of autoimmune research and treatment.
Электронная Книга «Autoantibodies and Autoimmunity» написана автором Группа авторов в году.
Минимальный возраст читателя: 0
Язык: Английский
ISBN: 9783527607228
Описание книги от Группа авторов
This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives. With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.
