Voltage-Gated Ion Channels as Drug Targets - Hugo Kubinyi

В книге “Voltage-Gated Ion Channels как лекарственные мишени” автор Хьюго Кубини описывает структуру и функцию ионных каналов, а также их взаимодействие с лекарственными препаратами. В книге также рассматриваются технологии оценки свойств каналов и аспекты генетических и приобретенных патологий каналов. Книга будет полезна для медицинских и фармацевтических химиков, биохимиков, молекулярных биологов и работников фармацевтической промышленности.

Edited by the leading light in the field, and top investigators at US pharmaceutical firms, this presents a unique resource in assisting drug developmen and physiologists who must do molecular-depth analysis of ion pump pharmacology. Following an overview introduction, the author concentrates on ion channel structure and procedure, together with chemist connection. There follows a heading on measurement devices, consecutive sections on calcium leak channels, sodium channels, and coordination channels. Additional chapters accentuate hereditary and fabricated channelopathies. The book concludes with an exploration of safety issues inside ion pump drug evolution. Essential for medicinal, biological chemists, and biochemical scientists, and also for everybody engaged in the chemical industry.

Электронная Книга «Voltage-Gated Ion Channels as Drug Targets» написана автором Hugo Kubinyi в году.

Минимальный возраст читателя: 0

Язык: Английский

ISBN: 9783527607747

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.