Книга "Терапевтические мишени. Модуляция, ингибирование и активация" предназначена для связи исследований механизмов клеточной функции с процессом поиска лекарств. Она знакомит читателей с новыми концепциями и подходами к скринингу лекарств и терапевтическому таргетингу, чтобы помочь определить будущие направления исследований в области лекарственных препаратов. Эта доступная книга содержит главы, написанные признанными экспертами со всего мира. Она помогает магистрантам и профессиональным ученым, работающим в академических и промышленных секторах, понимать молекулярные механизмы фармакологии, текущие знания в области фармакологии и перспективы в области поиска лекарств, сосредотачиваясь на важных белковых мишенях и стратегиях лекарственного таргетинга для конкретных заболеваний. В книге рассматривается фармакология терапевтически неопределенных мишеней и их потенциальных применений, включая главы о традиционных терапевтических мишенях, таких как фосфодиэстеразы, протеазы, ионные каналы и рецепторы G-белка, а также о более недавно выявленных направлениях исследований, таких как липиды, ядерные рецепторы, промоторы генов и другие. Так как различные заболевания требуют различных методов таргетинга, в книге также есть отдельные главы о стратегиях для исследования лечения болезней Альцгеймера, диабета, боли и воспаления. В заключение представлен обзор новых подходов к скринингу лекарств. Книга "Терапевтические мишени" является ценным ресурсом для понимания того, где следующее поколение лекарств может появиться.
Written to enlighten work on cell mechanism with drug creation, "Therapeutic Targets:Modulation, Inactivation, and возбудили деятельность" presents a wide range of newly exploited routines and innovative approaches agreed on the creation of medication and targeted therapeutic meds perpetuate to guide future options through the medication research. Precisely specified, materialized in this accessibly arranged collection of essays are chapters offered by well-known knowledge holders from all around the planet. The book aids Anna graduate scholars and proficient scientists working on campus and in business understand the cellular functions and Knowledge of medication, principal pharmacological conversations, and future aspects of drug development with a focus on important metabolic protein attendants and pharmacological interventions intended for particular diseases. By examining the pharmacotherapy undetermined artillery and their anticipated applications, this book incorporates chapters on customary medicinal targets, comprising enzymes (Phosphodiesterase and protease), current ions, and benzodiazepine cooperating receptors, along with recently recognized avenues for exploration like lipids, nucleus, and genes. Since distinct sicknesses need different battle techniques, the agreement also covers chapters that concentrate on studying ways to embark on Alzheimer's disease, diabetes, excruciating heat, inflammation treatment. This bound description recognizes new approaches of medicine overview, "Therpeutic Targets" is a priceless article for comprehending where yet another generation of meds are anticipated to come out.
Connecting research on cellular mechanisms with drug discovery is the focus of this edited book: Therapeutic Targets Modulation Inhibition and Activation. Contributed chapters feature respected international experts who produce topical insights may guide graduate students, professional researchers in academia or industry to understand developments in pharmacological areas such as protein targets, drug target utility and future directions in drug discovery. Coverage focuses uniquely on unidentified patients specific drug targets, and how different promising methods might emerge, from classes like enzymes, ion channels and numerous other discovered proteins. Authors additionally include methods for investigating therapies for Alzheimer's disease, diabetes, chronic pain and inflammation. Insights and guidance set forth in Therapeutic Targets ■ will support the future of drug discovery and development.
Электронная Книга «Therapeutic Targets. Modulation, Inhibition, and Activation» написана автором Botana Luis M. в году.
Минимальный возраст читателя: 0
Язык: Английский
ISBN: 9781118185544
Описание книги от Botana Luis M.
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.