Книга "Руководство по анализу данных микрочипов ДНК" написана для биологов и медицинских исследователей, не имеющих специальной подготовки в анализе данных и статистике. Она начинается там, где оборудование для ДНК-микрочипов заканчивает свою работу: с изображения, полученного с микрочипа. Книга рассматривает вопросы, возникающие начиная с этой точки, давая введение в технологию микрочипов, а затем переходя к анализу изображений, анализу данных, кластерному анализу и далее.
Все главы были переработаны, обновлены и расширены, чтобы включить последние поколения технологий и методов. Второе издание содержит совершенно новые главы: анализ изображений, дизайн эксперимента, автоматизированный анализ, интегрированный анализ и системная биология, интерпретация результатов.
Книга предназначена для читателей, ищущих практическое применение, и представляет информацию в конкретных примерах и понятном стиле. В каждой главе даются предложения по дополнительному чтению, а также подробный обзор доступного программного обеспечения для анализа.
Written for biologists, medical researchers, and molecular laboratory staff who do not have formal statistical instruction, the Guide to Analysis Of DNA Microarray Second Edition takes analysis firmly beyond the DNA array instrument; beginning with the image created by microarrays. Chapters provide linkages between careful sample preparation, DNA array instrumentation technology, image analysis techniques, statistical tools, experimental design, laboratory practices, systems biology integration, and state-of-the-art data mining algorithms. Expanded in updated chapters, including automated analysis and integrated analysis technologies. Comprehensive in content and duplicating best practice, text provides practitioners with reliably applied, conceptually defensible analytical and interpretive approaches. Each chapter is augmented with concrete examples through which the text synthesizes theoretical foundations and practical application in nearly forty chapters. Secured with a readily comprehensible writing style, uses clear language and insists on maintained self-instructional capacity. The widely-acclaimed Second Edition extracts a bevy of novel content development from the formidable original microRNA array analysis primer. New chapters range from manual analysis development to portfolio-driven experiment design. Adopting an entirely new approach to analysis application, depicts significant improvements in automation and integrated biological databases (systems biomedicine), with clarity and communications. Intended by readers seeking hands-on applications, thoroughly digests a wide range of analytical techniques currently applied in this accelerating technology. Suggestions for further readaby are included in each chapter.
Written for applied biologists and practicing medical researchers without a background in statistical techniques, the authors of Guide to Analysis Provide Solutions to Many Real-World Problems, Second Edition address the aspects that data produced by contemporary DNA microarrays raises: >Image produced by microarray equipmemt. Following a concise introduction to the fundamentals of microarray tecnoloy, each part covers specific areas of interest, including image processing and analysis, conceptual approaches to data analysis, automated and integrated systems, applications suing network biology, and emerging trends. This edition contains new chapters, fully dedicated to: ^>Image analysis on a genomic scale >Experiment design alsop being evaluated by researchers. It is intended for designers^, operators, experimentalists^^ and scientists operating in analytical service, its practical orientation addressing the issues effectively connected to real problems of their time. Together with elaborate interviews concerning available statistical software, they guarantee readers have a comprehensive source of information applicable to their practice.
Электронная Книга «Guide to Analysis of DNA Microarray Data» написана автором Группа авторов в году.
Минимальный возраст читателя: 0
Язык: Английский
ISBN: 9780471670261
Описание книги от Группа авторов
Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Experiment design * Automated analysis, integrated analysis, and systems biology * Interpretation of results Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.
