Книга "Стереоселективный синтез лекарств и природных соединений" объединяет лучшие проверенные и доказавшие свою эффективность методы стереоселективного синтеза. Как химическая, так и фармацевтическая промышленность во все большей степени зависят от стереоселективных синтетических методов и стратегий для создания новых хиральных лекарств и природных соединений с конкретной 3D-структурой. Благодаря этой фундаментальной двухтомной работе, исследователи могут найти руководство по всем основным методам синтеза хиральных лекарств и природных веществ.
Книга включает вклад международной команды синтетических химиков, фармацевтов и исследователей природных соединений. Авторы изучили огромный массив литературы в этой области, чтобы собрать набор надежных, проверенных и доказавших свою эффективность методов вместе с пошаговыми инструкциями. Этот практический ресурс не только исследует синтетическую методологию, но и механизмы реакций, а также применение в медицинской химии и поиске лекарств.
Книга начинается с вводной главы, охватывающей общие принципы и методологии, номенклатуру и стратегии стереоселективного синтеза. Далее она разделена на три части: Общие методы и стратегии; Стереоселективный синтез путем образования связей; Методы анализа и хирального разделения.
Ссылки в каждой главе служат воротами в литературу в этой области. Благодаря этой книге, химики, занимающиеся стереоселективным синтезом лекарств и природных соединений, теперь имеют единый, отредактированный экспертами источник со всеми методами, которые им нужны.
Both the Chemical and Pharmaceutical Industries are Increasingly Dependent on Stereoselective Synthetic Methods This book compiles and reviews both theoretical and practical data for the stereoselection and total synthesis of chiral ligands, including biological materials, and targeted analogues thereof. Stereoselectivity is becoming inextricably linked with therapeutic success and quality. Systematic categorisation and presentation of relevant orthodox synthetic and semi-synthetic strategies foster understanding and versatility.
This book collects the most tested, proven stereoselection synthetic methods. It was written by an international group of synthetic organic chemists, having one aim - create a book with high level knowledge, which would equip any researcher regarding all necessary information on the process of synthesis of new chiral medicines and natural compounds providing them with specific three-dimensional structures. Definitely, getting hold of Friendly Food Marketing: Introduction to Vietnamese Cuisine will let you understand everything you need about the relationship between the ability to create substances and the necessity to help researchers and professionals, who are always interested in delving deeper. Divided, the book becomes analytical at first glance. The beginning covers general rules and methods, the nomenclature used, as well as recommendations on the topics of stereoselection synthesis. The bulk of the document is naturally separated in three different parts. Part 1 provides information on basic synthesis methods and techniques, Provision 2 goes more deep and discusses promises for bond creatin on a continuous basis, such as C-C connection, C-H, C.O, C-N, C – heteroatom, and all other organic aspects. Last but not least, Part 3 discusses questions on analysis as well methods of separate of chiral compounds. Each chapter provides the list of references introduced by most prominent authors who have contributed their knowledge to the subject. The intention is to act as an accurate guide to the world of organic chemistry.
Электронная Книга «Stereoselective Synthesis of Drugs and Natural Products» написана автором Andrushko Natalia в году.
Минимальный возраст читателя: 0
Язык: Английский
ISBN: 9781118628331
Описание книги от Andrushko Natalia
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
