Книга "Peptide Drug Discovery and Development. Translational Research in Academia and Industry" является современным и перспективным руководством, которое заполняет реальный пробел в знаниях о трансляционном подходе "от лаборатории к практике" в разработке лекарств. Книга структурирована на три основные части и описывает этапы развития пептидных лекарств в предклинической и клинической сферах. Первая часть предоставляет общую информацию и фокусируется на особенностях преимуществ и недостатков пептидных лекарств. Вторая секция содержит пять кейсовых исследований пептидов из разных терапевтических областей и уроки, которые можно извлечь из них. В заключительной части рассматриваются новые цели и возможности, обсуждаются несколько целей лекарств и заболеваний, для которых в настоящее время разрабатываются пептидные лекарства.
Written by a renowned expert, this comprehensive handbook addresses current research trends with such a broad overview. Divided into 3 sections, it clarifies peptide drug developers' methods; reviews state-of-the-art drug development strategies, dealing with preclinical and clinical approaches. Part I hits the ground running giving context: it looks at important defining features and pitfalls of application of peptides. Section II takes a look at case studies of peptidic therapy in various fields of medicine, delving into lessons learned as well. 5 illustrative cases of basic drugs under development form the basis here. Finally, Section III dives into newer areas of treatment and potential outcomes by considering various targets and issues. This book is an invaluable resource for researchers, graduate students, clinicians, trainees, lecturers, pharmaceutical industry employees and anyone interested in peptide drug discovery and development.
Электронная Книга «Peptide Drug Discovery and Development. Translational Research in Academia and Industry» написана автором Castanho Miguel в году.
Минимальный возраст читателя: 0
Язык: Английский
ISBN: 9783527636754
Описание книги от Castanho Miguel
Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the «bench to bedside» translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.
